Property, Plant and Equipment, Net (Details) ft² in Thousands, $ in Thousands	3 Months Ended
	Jun. 30, 2019 USD ($) ft²	Sep. 30, 2019 USD ($)	Dec. 31, 2018 USD ($)
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		$ 67,232	$ 66,050
Less: Accumulated depreciation		(8,955)	(5,525)
Property, plant and equipment, net		58,277	60,525
Build-to-suit lease obligation derecognized	$ 4,400
Build-to-suit, long term obligation			4,500
Ireland
Property, Plant and Equipment [Line Items]
Area of interior floor space (in sqft) | ft²	30
Manufacturing equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		17,992	2,366
Laboratory equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		7,374	6,038
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		1,648	1,815
Software, computer and other equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		6,567	2,702
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		29,671	4,072
Construction-in-progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross		$ 3,980	$ 49,057