Property, Plant and Equipment, Net (Details) ft² in Thousands, $ in Thousands	3 Months Ended
	Jun. 30, 2019 USD ($) ft²	Dec. 31, 2018 USD ($)
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 65,968	$ 66,050
Less: Accumulated depreciation	(7,373)	(5,525)
Property, plant and equipment, net	58,595	60,525
Build-to-suit lease obligation derecognized	4,400
Build-to-suit, long term obligation		4,500
Manufacturing equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	17,773	2,366
Laboratory equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	7,169	6,038
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	1,620	1,815
Software, computer and other equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	6,550	2,702
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	29,511	4,072
Construction-in-progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 3,345	$ 49,057
Ireland
Property, Plant and Equipment [Line Items]
Area of interior floor space (in sqft) | ft²	30