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Accrued Expenses and Other Current Liabilities (Tables)
6 Months Ended
Jun. 30, 2019
Payables and Accruals [Abstract]  
Summary of Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities consist of the following:
 
(in thousands)
JUNE 30, 2019
 
DECEMBER 31, 2018
Accrued compensation and benefits
$
8,269

 
$
10,438

Accrued consulting and professional fees
3,009

 
3,927

Accrued research and development expenses (1)
7,673

 
7,503

Accrued revenue reserves
26,047

 
10,155

Accrued other (2)
1,525

 
6,358

Total accrued expenses and other current liabilities
$
46,523

 
$
38,381

 
(1) 
Comprised of accruals related to fees for investigative sites, contract research organizations, contract manufacturing organizations and other service providers that assist in conducting preclinical research studies and clinical trials.
(2) 
Comprised of accruals related to commercial manufacturing activities for the Company’s product candidates prior to receipt of regulatory approval, as well as other business-related expenses.