Accrued Expenses & Other Current Liabilities (Tables)

12 Months Ended

Dec. 31, 2018

Payables and Accruals [Abstract]

Summary of Accrued Expenses & Other Current Liabilities

Accrued expenses and other current liabilities consist of the following:

	DECEMBER 31,
(in thousands)	2018		2017
Accrued expenses and other current liabilities:
Accrued compensation and benefits	$	10,438	$	7,886
Accrued consulting and professional fees	3,927		3,841
Accrued research and development (1)	7,503		1,855
Accrued revenue reserves	10,155		—
Accrued other(2)	6,358		5,357
Total accrued expenses and other current liabilities	$	38,381	$	18,939

(1) Comprised of accruals related to fees for investigative sites, contract research organizations, contract manufacturing organizations and other service providers that assist in conducting preclinical research studies and clinical trials.

(2) Comprised of accruals related to commercial manufacturing activities for the Company’s product candidates prior to the receipt of regulatory approval, as well as other business-related expenses.