Property, Plant and Equipment, Net (Tables)

12 Months Ended

Dec. 31, 2018

Property, Plant and Equipment [Abstract]

Schedule of Property, Plant and Equipment, Net

Estimated useful lives by major asset category are as follows:

Manufacturing equipment	10 years
Laboratory equipment	7 years
Furniture and fixtures	5 years
Software, computer and other equipment	3 years
Leasehold improvements	Lower of estimated useful life or term of lease

Property, plant and equipment, net consists of the following:

(in thousands)	DECEMBER 31,
	2018			2017
Manufacturing equipment	$	2,366		$	2,082
Laboratory equipment	6,038			3,602
Furniture and fixtures	1,815			1,209
Software, computer and other equipment	2,702			1,932
Leasehold improvements	4,072			1,887
Construction-in-progress	49,057			24,228
Property, plant and equipment	66,050			34,940
Less: Accumulated depreciation	(5,525		)	(3,008		)
Property, plant and equipment, net	$	60,525		$	31,932

Schedule of Minimum Expected Lease Payments

Minimum expected lease payments were as follows at December 31, 2018^(a):

(in thousands)
2019	$	250
2020	250
2021	250
2022	259
2023	286
2024 and thereafter	1,219
Total minimum lease payments (b)	$	2,514

(a) Uses foreign exchange rates in effect at December 31, 2018.

(b) This represents the obligation through the minimum lease term of September 2027. If the Company utilizes the leased space through the full term of the lease, expiring in September 2037, the total rental payments would be $5.9 million.