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The Company (Detail)			3 Months Ended		9 Months Ended
The Company (Detail)	Dec. 31, 2020 USD ($)	Aug. 01, 2018 USD ($)	Sep. 30, 2018 USD ($)	Sep. 30, 2017 USD ($)	Sep. 30, 2018 USD ($) Segment	Sep. 30, 2017 USD ($)	Jul. 23, 2018 USD ($)	Dec. 31, 2017 USD ($)	Sep. 30, 2014 USD ($)
Organization, Consolidation and Presentation of Financial Statements [Line Items]
Number of operating segments \| Segment					1
Research and development expense			$ 28,502,000	$ 12,408,000	$ 59,631,000	$ 33,977,000
Aggregate amount of senior notes issued								$ 125,000,000
Induced conversion, expense recognized			24,100,000
2014 Notes \| 2014 Convertible Notes
Organization, Consolidation and Presentation of Financial Statements [Line Items]
Aggregate amount of senior notes issued								$ 125,000,000	$ 125,000,000
Revolving Credit Facility \| Delayed Draw Term Loan
Organization, Consolidation and Presentation of Financial Statements [Line Items]
Maximum borrowing capacity							$ 100,000,000
Collaborative Arrangement
Organization, Consolidation and Presentation of Financial Statements [Line Items]
Amount paid upon execution of collaboration agreement		$ 6,000,000
Research and development expense			$ 7,400,000
Collaborative Arrangement \| Scenario, Forecast
Organization, Consolidation and Presentation of Financial Statements [Line Items]
Amount payable on collaborative arrangement	$ 9,000,000