Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2018

Accounting Policies [Abstract]

Schedule of Estimated Useful Lives

Estimated useful lives by major asset category are as follows:

Manufacturing equipment	10 years
Laboratory equipment	7 years
Furniture and fixtures	5 years
Software and computer equipment	3 years
Leasehold improvements	Lower of estimated useful life or term of lease

Property, plant and equipment, net consists of the following:

(in thousands)	SEPTEMBER 30, 2018			DECEMBER 31, 2017
Manufacturing equipment	$	2,307		$	2,082
Laboratory equipment	4,915			3,602
Furniture and fixtures	1,536			1,209
Software and computer equipment	2,321			1,932
Leasehold improvements	3,685			1,887
Construction-in-progress	48,416			24,228
	63,180			34,940
Less: Accumulated depreciation	(4,820		)	(3,008		)
Total property, plant and equipment, net	$	58,360		$	31,932

Schedule of Computation of Diluted EPS

The potential common stock equivalents that have been excluded from the computation of Diluted EPS consist of the following:

	THREE MONTHS ENDED   SEPTEMBER 30,		NINE MONTHS ENDED   SEPTEMBER 30,
	2018	2017	2018	2017
2014 Convertible Notes	—	5,040,323	—	5,040,323
Outstanding stock options	6,951,639	6,237,959	6,951,639	6,237,959
Stock purchase warrants	154,500	157,500	154,500	157,500
Nonvested restricted stock awards	584,124	439,549	584,124	439,549
Total	7,690,263	11,875,331	7,690,263	11,875,331