Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Revenues	$ 2,423,000	$ 0	$ 2,423,000	$ 0
Costs and expenses:
Cost of goods sold	59,000	0	59,000	0
Selling, general and administrative	39,891,000	17,153,000	67,714,000	31,628,000
Research and development	18,157,000	10,615,000	31,129,000	21,569,000
Total costs and expenses	58,107,000	27,768,000	98,902,000	53,197,000
Loss from operations	(55,684,000)	(27,768,000)	(96,479,000)	(53,197,000)
Other income (expense), net	663,000	(618,000)	759,000	(930,000)
Loss before income taxes	(55,021,000)	(28,386,000)	(95,720,000)	(54,127,000)
Income tax expense	3,000	47,000	3,000	93,000
Net loss	$ (55,024,000)	$ (28,433,000)	$ (95,723,000)	$ (54,220,000)
Net loss per common share—basic and diluted (in dollars per share)	$ (1.40)	$ (0.82)	$ (2.46)	$ (1.58)
Weighted average number of common shares outstanding—basic and diluted (in shares)	39,204,762	34,783,195	38,903,469	34,283,073
Net loss	$ (55,024,000)	$ (28,433,000)	$ (95,723,000)	$ (54,220,000)
Unrealized gain (loss) on available-for-sale investments	148,000	24,000	19,000	(13,000)
Comprehensive loss	(54,876,000)	(28,409,000)	(95,704,000)	(54,233,000)
Product revenues, net
Revenues	$ 2,423,000	$ 0	$ 2,423,000	$ 0