Property, Plant and Equipment, Net (Tables)

6 Months Ended

Jun. 30, 2018

Property, Plant and Equipment [Abstract]

Schedule of Property, Plant and Equipment

Estimated useful lives by major asset category are as follows:

Manufacturing equipment	10 years
Laboratory equipment	7 years
Furniture and fixtures	5 years
Software and computer equipment	3 years
Leasehold improvements	Lower of estimated useful life or term of lease

Property, plant and equipment, net consists of the following:

(in thousands)	JUNE 30, 2018			DECEMBER 31, 2017
Manufacturing equipment	$	2,122		$	2,082
Laboratory equipment	4,404			3,602
Furniture and fixtures	1,512			1,209
Software and computer equipment	2,218			1,932
Leasehold improvements	3,318			1,887
Construction-in-progress	45,449			24,228
	59,023			34,940
Less: Accumulated depreciation	(4,144		)	(3,008		)
Total property, plant and equipment, net	$	54,879		$	31,932