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The Company The Company (Details)
$ in Thousands
12 Months Ended
Oct. 04, 2017
USD ($)
shares
Dec. 31, 2017
USD ($)
Segment
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Organization, Consolidation and Presentation of Financial Statements [Line Items]        
Number of business segments | Segment   1    
Research and development $ 24,802 $ 72,078 $ 52,394 $ 44,451
Rhopressa        
Organization, Consolidation and Presentation of Financial Statements [Line Items]        
Percentage of dosage designed to reduce elevated intraocular pressure   0.02%    
Latanoprost        
Organization, Consolidation and Presentation of Financial Statements [Line Items]        
Percentage of dosage designed to reduce elevated intraocular pressure   0.005%    
Envisia Therapeutics Inc.        
Organization, Consolidation and Presentation of Financial Statements [Line Items]        
Upfront cash payment $ 10,500      
Stock issued during period (in shares) | shares 263,146      
Stock issued during period, value $ 14,300      
Milestone payments contingent upon the achievement of certain approvals $ 45,000