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Significant Accounting Policies - Schedule of Computation of Diluted EPS (Details) - shares
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Convertible notes payable      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potential common stock equivalents excluded from the computation of diluted net loss per share 5,040,323 5,040,323 0
Outstanding stock options      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potential common stock equivalents excluded from the computation of diluted net loss per share 4,583,586 3,826,459 3,189,660
Stock purchase warrants      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potential common stock equivalents excluded from the computation of diluted net loss per share 157,500 309,506 309,506
Restricted common stock awards      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potential common stock equivalents excluded from the computation of diluted net loss per share 119,993 103,064 246,068