Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities
Net loss	$ (82,088)	$ (120,343)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities
Depreciation	4,802	4,774
Amortization and accretion	5,582	22,943
Stock-based compensation	12,232	23,358
Other non-cash	(505)	1,221
Changes in operating assets and liabilities
Accounts receivable, net	(5,053)	(8,544)
Inventory	(5,548)	(2,486)
Prepaid, current, and other assets	6,938	(5,381)
Licensing receivable	90,000	0
Accounts payable, accrued expenses, and other current liabilities	7,692	14,738
Operating lease liabilities	(3,341)	(2,165)
Deferred revenue	6,566	2,841
Net cash provided by (used in) operating activities	37,277	(69,044)
Cash flows from investing activities
Purchase of available-for-sale investments	(145,726)	(112,432)
Proceeds from sales and maturities of investments	129,137	94,708
Purchase of property, plant, and equipment	(3,779)	(2,540)
Net cash used in investing activities	(20,368)	(20,264)
Cash flows from financing activities
Payments related to issuance of stock for stock-based compensation arrangements, net	(3)	(415)
Net cash used in financing activities	(3)	(415)
Net change in cash and cash equivalents	16,906	(89,723)
Cash and cash equivalents, at beginning of period	37,187	151,570
Cash and cash equivalents, at end of period	54,093	61,847
Non-cash investing and financing activities
Purchase of property, plant, and equipment in accounts payable and accrued expenses and other current liabilities	$ 947	$ 200