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Significant Accounting Policies - Computation of Diluted EPS (Details) - shares
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 20,134,015 9,654,960 20,134,015 9,654,960
Convertible Notes        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 12,662,650 0 12,662,650 0
Outstanding stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 5,753,892 8,703,221 5,753,892 8,703,221
Non-vested restricted stock awards        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 1,491,788 796,656 1,491,788 796,656
Non-vested restricted stock units        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 225,685 155,083 225,685 155,083