Revenue Recognition - Deferred Revenue, Noncurrent (Details) - USD ($) $ in Thousands	Jun. 30, 2022	Jan. 31, 2022	Dec. 31, 2021	Oct. 31, 2020
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current	$ 70,438		$ 64,315
Second Santen Agreement | License Revenue, Upfront Payment
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current		$ 90,000	88,000	$ 50,000
Santen
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current	70,438		64,315
Santen | First Santen Agreement | License Revenue, Upfront Payment
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current	50,000		50,000
Santen | First Santen Agreement | License Revenue, Developmental Milestones
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current	6,000		0
Santen | First Santen Agreement | License Revenue, Counterparty's Portion Of Costs
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current	6,438		6,315
Santen | Second Santen Agreement | License Revenue, Upfront Payment
Disaggregation of Revenue [Line Items]
Deferred revenue, non-current	$ 8,000		$ 8,000