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Significant Accounting Policies - Computation of Diluted EPS (Details) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 19,943,260 9,509,572 19,943,260 9,509,572
Convertible Notes        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 12,662,650 0 12,662,650 0
Outstanding stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 6,067,388 8,720,650 6,067,388 8,720,650
Non-vested restricted stock awards        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 1,080,902 692,180 1,080,902 692,180
Non-vested restricted stock units        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potential common stock equivalents excluded from the computation of diluted net loss per share (in shares) 132,320 96,742 132,320 96,742