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Stock-Based Compensation (Tables)
 6 Months Ended
Jun. 30, 2022
Share-Based Payment Arrangement [Abstract]  
Schedule of Stock-Based Compensation Expense
Stock-based compensation expense for options granted, restricted stock awards (“RSAs”), RSAs with non-market performance and service conditions (“PSAs”), restricted stock units (“RSUs”), and stock appreciation rights (“SARs”) is reflected in the condensed consolidated statements of operations and comprehensive loss as follows:
 THREE MONTHS ENDED 
JUNE 30,		SIX MONTHS ENDED 
JUNE 30,
(in thousands)2022202120222021
Cost of goods sold$70 $431 $232 $938 
Selling, general, and administrative2,636 5,598 5,770 11,853 
Research and development1,252 1,967 2,588 3,954 
Total$3,958 $7,996 $8,590 $16,745 
Schedule of Stock Options Activity
The following table summarizes the stock option activity under the Plans:
NUMBER OF
SHARES		WEIGHTED
 AVERAGE EXERCISE PRICE		WEIGHTED
AVERAGE
REMAINING
CONTRACTUAL
LIFE (YEARS)		AGGREGATE
INTRINSIC
VALUE
(000’s)
Options outstanding at December 31, 2021
6,550,610 $26.87 
Granted803,512 8.37 
Canceled(1,286,734)26.53 
Options outstanding at June 30, 2022
6,067,388 $24.49 5.94$1,408 
Options exercisable at June 30, 2022
4,013,433 $30.37 4.36$1,255 
Options vested and expected to vest at June 30, 2022
6,067,388 $24.49 5.94$1,408 
Schedule of Share-based Compensation, Restricted Stock and Restricted Stock Units Activity
The following table summarizes the RSA, including PSA, activity under the Plans:
NUMBER OF
SHARES		WEIGHTED AVERAGE
FAIR VALUE PER SHARE
Non-vested RSAs at December 31, 2021
977,244 $18.32 
Granted385,866 8.52 
Vested(151,174)32.44 
Canceled(131,034)19.33 
Non-vested RSAs at June 30, 2022
1,080,902 12.72 
The following table summarizes the RSU activity under the Plans:
NUMBER OF
SHARES		WEIGHTED AVERAGE
FAIR VALUE PER SHARE
Non-vested RSUs at December 31, 2021
156,873 $14.88 
Granted2,571 7.37 
Vested(7,920)6.89 
Canceled(19,204)15.33 
Non-vested RSUs at June 30, 2022
132,320 15.15 
Schedule of Stock Appreciation Rights
The following table summarizes the SARs activity under the Plans:
NUMBER OF
SHARES		WEIGHTED 
AVERAGE
EXERCISE PRICE		WEIGHTED
AVERAGE
REMAINING
CONTRACTUAL
LIFE (YEARS)		AGGREGATE
INTRINSIC
VALUE
(000’s)
SARs outstanding at December 31, 2021
238,349 $27.67 
Granted11,000 7.59 
Canceled(30,116)29.36 
SARs outstanding at June 30, 2022
219,233 $64.62 2.67$2 
SARs exercisable at June 30, 2022
95,306 $38.62 1.66$—