Accrued Expenses and Other Current Liabilities (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Accrued expenses and other current liabilities:
Accrued compensation and benefits	$ 11,855	$ 15,881
Accrued consulting and professional fees	3,976	5,007
Accrued research and development	3,089	2,262
Accrued revenue reserves	79,213	85,381
Accrued other	4,817	3,810
Total accrued expenses and other current liabilities	$ 102,950	$ 112,341