Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2021

Accounting Policies [Abstract]

Schedule of Estimated Useful Lives

Estimated useful lives by major asset category are as follows:

Manufacturing equipment	10 years
Laboratory equipment	7 years
Furniture and fixtures	5 years
Software, computer and other equipment	3 years
Leasehold improvements	Lower of estimated useful life or term of lease

Property, plant and equipment, net consists of the following:

(in thousands)	DECEMBER 31,
	2021		2020
Manufacturing equipment	$	22,464	$	21,705
Laboratory equipment	9,182		7,948
Furniture and fixtures	1,569		1,681
Software, computer and other equipment	7,779		7,836
Leasehold improvements	31,175		30,178
Construction-in-progress	2,037		1,481
Property, plant and equipment	74,206		70,829
Less: Accumulated depreciation	(22,734)		(16,569)
Property, plant and equipment, net	$	51,472	$	54,260

Schedule of Computation of Diluted EPS

The potential common stock equivalents that have been excluded from the computation of Diluted EPS consist of the following:

	DECEMBER 31,
	2021	2020	2019
Outstanding stock options	6,550,610	8,588,614	8,425,551
Stock purchase warrants	—	—	4,500
Nonvested restricted stock awards	977,244	809,527	754,415
Nonvested restricted stock units	156,873	107,182	41,811
Total	7,684,727	9,505,323	9,226,277