Property, Plant and Equipment, Net

12 Months Ended

Dec. 31, 2021

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment, Net

Property, Plant and Equipment, Net

Property, plant and equipment, net consists of the following:

(in thousands)	DECEMBER 31,
	2021		2020
Manufacturing equipment	$	22,464	$	21,705
Laboratory equipment	9,182		7,948
Furniture and fixtures	1,569		1,681
Software, computer and other equipment	7,779		7,836
Leasehold improvements	31,175		30,178
Construction-in-progress	2,037		1,481
Property, plant and equipment	74,206		70,829
Less: Accumulated depreciation	(22,734)		(16,569)
Property, plant and equipment, net	$	51,472	$	54,260

Depreciation expense was $6.4 million, $6.4 million and $5.1 million for the years ended December 31, 2021, 2020 and 2019, respectively.