X0306 4 2021-12-20 0 0001337553 AERIE PHARMACEUTICALS INC AERI 0001778539 KANNAN RAJ C/O AERIE PHARMACEUTICALS, INC. 4301 EMPEROR BLVD., SUITE 400 DURHAM NC 27703 1 1 0 0 Chief Executive Officer Common Stock 2021-12-20 4 A 0 215783 0.00 A 215783 D Stock Option (right to buy) 8.11 2021-12-20 4 A 0 387169 0.00 A 2031-12-20 Common Stock 387169 387169 D These shares of Common Stock were granted under the Aerie Pharmaceuticals, Inc. Amended and Restated Inducement Award Plan (the "Plan") and are scheduled to vest, subject to the reporting person's continued employment with the issuer through the applicable vesting date, in equal installments on each of the first four anniversaries of December 20, 2021. This option was granted under the Plan and is scheduled to vest, subject to the reporting person's continued employment with the issuer through the applicable vesting date, as to 25% of the underlying shares on December 20, 2022 and as to the remaining underlying shares in substantially equal installments on each of the subsequent 36 monthly anniversaries of December 20, 2022. /s/ Raj Kannan 2021-12-22