X0306 4 2021-02-04 0 0001337553 AERIE PHARMACEUTICALS INC AERI 0001207633 ANIDO VICENTE JR C/O AERIE PHARMACEUTICALS, INC. 4301 EMPEROR BLVD., SUITE 400 DURHAM NC 27703 1 1 0 0 Chief Executive Officer Common Stock 2021-02-04 4 A 0 28000 0.00 A 243050 D Common Stock 10500 I Spouse IRA Stock Option (right to buy) 17.64 2021-02-04 4 A 0 125000 0.00 A 2031-02-04 Common Stock 125000 125000 D These shares of Common Stock are scheduled to vest, subject to the reporting person's continued employment with the issuer through the applicable vesting date, in equal installments on each of the first four anniversaries of February 4, 2021. This option is scheduled to vest, subject to the reporting person's continued employment with the issuer through the applicable vesting date, in equal installments on each of the first 48 monthly anniversaries of February 4, 2021. /s/ John LaRocca, Attorney-in-Fact for Vicente Anido, Jr. 2021-02-08