X0306 4 2018-06-06 0 0001337553 AERIE PHARMACEUTICALS INC AERI 0001590001 Kopczynski Casey C. C/O AERIE PHARMACEUTICALS, INC. 4301 EMPEROR BLVD., SUITE 400 DURHAM NC 27703 0 1 0 0 Chief Scientific Officer Common Stock 2018-06-06 4 S 0 8000 58.5744 D 183517 D Common Stock 2018-06-06 4 S 0 3000 59.2138 D 180517 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.10 to $59.00, inclusive. The reporting person undertakes to provide the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the footnotes to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.15 to $59.25, inclusive. /s/ Richard J. Rubino, Attorney-in-Fact for Casey C. Kopczynski 2018-06-08