X0306 4 2018-05-21 0 0001337553 AERIE PHARMACEUTICALS INC AERI 0001589991 Cagle Gerald D. C/O AERIE PHARMACEUTICALS, INC. 4301 EMPEROR BLVD., SUITE 400 DURHAM NC 27703 1 0 0 0 Common Stock 2018-05-21 4 P 0 1000 50.245 A 15050 D /s/ Richard J. Rubino, Attorney-in-Fact for Gerald D. Cagle 2018-05-22