X0306 4 2017-02-23 0 0001337553 AERIE PHARMACEUTICALS INC AERI 0001216984 MITRO THOMAS A C/O AERIE PHARMACEUTICALS, INC. 2030 MAIN STREET, SUITE 1500 IRVINE CA 92614 0 1 0 0 President and COO Common Stock 2017-02-23 4 A 0 8824 0.00 A 36274 D Common Stock 2017-02-24 4 F 0 1116 44.55 D 35158 D Common Stock 2017-02-25 4 F 0 1116 44.55 D 34042 D Stock Option (right to buy) 44.25 2017-02-23 4 A 0 79418 0.00 A 2027-02-23 Common Stock 79418 79418 D These shares of Common Stock are scheduled to vest, subject to the reporting person's continued employment with the issuer through the applicable vesting date, in equal installments on each of the first four anniversaries of February 23, 2017. This option is scheduled to vest, subject to the reporting person's continued employment with the issuer through the applicable vesting date, in equal installments on each of the first 48 monthly anniversaries of February 23, 2017. /s/ Richard J. Rubino, Attorney-in-Fact for Thomas A. Mitro 2017-02-27