X0306 4 2019-03-28 0001337013 InfuSystem Holdings, Inc INFU 0001768484 RUIZ THOMAS MARK 31700 RESEARCH PARK DRIVE MADISON HEIGHTS MI 48071 1 VP OF SALES AND MARKETING Common Stock 2019-03-28 4 M 0 2083 A 7420 D Common Stock 2019-03-28 4 F 0 584 4.14 D 6836 D Restricted Stock Units 2019-03-28 4 M 0 2083 0 D Common Stock 2083 0 D Represents the acquisition of the Issuer's common stock by reporting person pursuant to the vesting and settlement of a one remaining portion of the restricted stock units (RSUs) granted on March 11, 2015. Restricted stock units convert into common stock on a one-for-one basis. Represents the withholding of the Issuer's common stock for the tax liability associated with the vesting and settlement of one remaining portion of the restricted stock units (RSUs) granted on March 11, 2015. /s/ Thomas M. Ruiz 2019-04-01