X0306 4 2021-02-09 0 0001337013 InfuSystem Holdings, Inc INFU 0001790024 Lachance Carrie 3851 WEST HAMLIN ROAD ROCHESTER HILLS MI 48309 0 1 0 0 Executive VP and COO Common Stock 2021-02-09 4 A 0 4017 0 A 84956 D The reported shares were issued as part of the issuer's Short Term Incentive ("STI") plan relating to the issuer's 2020 performance. The issuer's board of directors decided that a portion of the award determined payable to the issuer's executive team would be payable in the form of fully-vested shares of the issuer's common stock. Such shares are issued under the issuer's 2014 Equity Plan. This total includes an additional 1,146 shares acquired recently through the Company's Employee Stock Purchase Plan. /s/Kevin Whitman, Attorney-in-Fact for Carrie Lachance 2021-02-11