X0306 4 2020-09-30 0 0001337013 InfuSystem Holdings, Inc INFU 0001768484 RUIZ THOMAS MARK 3851 WEST HAMLIN ROAD ROCHESTER HILLS MI 48309 0 1 0 0 Chief Commercial Officer Common Stock 2020-09-30 4 S 0 64745 11.95 D 963 D The price reported in Column 4 is a weighted average price. These shares reported herein were sold in multiple transactions. The reporting person undertakes to provide to the Issuer, and security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price. /s/Kevin Whitman, Attorney-in-Fact for Thomas Ruiz 2020-10-02