0001172661-23-003047.txt : 20230814 0001172661-23-003047.hdr.sgml : 20230814 20230814101445 ACCESSION NUMBER: 0001172661-23-003047 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20230630 FILED AS OF DATE: 20230814 DATE AS OF CHANGE: 20230814 EFFECTIVENESS DATE: 20230814 FILER: COMPANY DATA: COMPANY CONFORMED NAME: HighVista Strategies LLC CENTRAL INDEX KEY: 0001335325 IRS NUMBER: 830423786 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-14212 FILM NUMBER: 231167031 BUSINESS ADDRESS: STREET 1: 200 CLARENDON STREET, 50TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 617-406-6520 MAIL ADDRESS: STREET 1: 200 CLARENDON STREET, 50TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001335325 XXXXXXXX 06-30-2023 06-30-2023 false HighVista Strategies LLC

200 CLARENDON STREET, 50TH FLOOR BOSTON MA 02116

13F HOLDINGS REPORT 028-14212 000155759 801-73524 N Ron Landen 617-406-6548 /s/ Ronald A. Landen Boston MA 08-14-2023 0 134 218561127 INFORMATION TABLE 2 q201813f.inftab.xml 89BIO INC COM 282559103 826959 43639 SH SOLE 43639 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 689544 28791 SH SOLE 28791 0 0 ACLARIS THERAPEUTICS INC COM 00461U105 892888 86103 SH SOLE 86103 0 0 ACTIVISION BLIZZARD INC COM 00507V109 5186136 61520 SH SOLE 61520 0 0 ADOBE SYSTEMS INCORPORATED COM 00724F101 696811 1425 SH SOLE 1425 0 0 AEROJET ROCKETDYNE HLDGS INC COM 007800105 3375602 61520 SH SOLE 61520 0 0 AEROVATE THERAPEUTICS INC COM 008064107 716921 41803 SH SOLE 41803 0 0 ALBERTSONS COS INC COMMON STOCK 013091103 4118590 188753 SH SOLE 188753 0 0 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 654881 7857 SH SOLE 7857 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 770397 4056 SH SOLE 4056 0 0 ALPHABET INC CAP STK CL C 02079K107 2665695 22036 SH SOLE 22036 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 928150 90287 SH SOLE 90287 0 0 AMAZON COM INC COM 023135106 1341795 10293 SH SOLE 10293 0 0 AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 2525474 153431 SH SOLE 153431 0 0 AMICUS THERAPEUTICS INC COM 03152W109 786017 62581 SH SOLE 62581 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 296544 13748 SH SOLE 13748 0 0 ANAPTYSBIO INC COM 032724106 765821 37651 SH SOLE 37651 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 2755046 30242 SH SOLE 30242 0 0 APOLLO GLOBAL MGMT INC COM 03769M106 957513 12466 SH SOLE 12466 0 0 ARCELLX INC COMMON STOCK 03940C100 1987918 62869 SH SOLE 62869 0 0 ARGENX SE SPONSORED ADR 04016X101 692940 1778 SH SOLE 1778 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 372619 4175 SH SOLE 4175 0 0 AUTOLIV INC COM 052800109 496974 5844 SH SOLE 5844 0 0 AXSOME THERAPEUTICS INC COM 05464T104 3549884 49400 SH SOLE 49400 0 0 BAIDU INC SPON ADR REP A 056752108 792161 5786 SH SOLE 5786 0 0 BAUSCH HEALTH COS INC COM 071734107 786808 98351 SH SOLE 98351 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 2358916 92434 SH SOLE 92434 0 0 BILIBILI INC SPONS ADS REP Z 090040106 1220941 80857 SH SOLE 80857 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 483824 68725 SH SOLE 68725 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 692833 7993 SH SOLE 7993 0 0 BIOMEA FUSION INC COM 09077A106 825320 37600 SH SOLE 37600 0 0 BLACK KNIGHT INC COM 09215C105 3591027 60121 SH SOLE 60121 0 0 BOOKING HOLDINGS INC COM 09857L108 964018 357 SH SOLE 357 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 839496 24742 SH SOLE 24742 0 0 CHARTER COMMUNICATIONS INC N CL A 16119P108 710494 1934 SH SOLE 1934 0 0 CHESAPEAKE ENERGY CORP COM 165167735 662411 7916 SH SOLE 7916 0 0 CHINOOK THERAPEUTICS INC COM 16961L106 2920727 76021 SH SOLE 76021 0 0 CIVITAS RESOURCES INC COM NEW 17888H103 683225 9849 SH SOLE 9849 0 0 COGENT BIOSCIENCES INC COM 19240Q201 2558979 216130 SH SOLE 216130 0 0 CONSTELLIUM SE CL A SHS F21107101 510737 29694 SH SOLE 29694 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 587866 32623 SH SOLE 32623 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 3710320 338842 SH SOLE 338842 0 0 DICE THERAPEUTICS INC COM 23345J104 1001538 21557 SH SOLE 21557 0 0 DROPBOX INC CL A 26210C104 674484 25290 SH SOLE 25290 0 0 DUOLINGO INC CL A COM 26603R106 781453 5467 SH SOLE 5467 0 0 ENLIVEN THERAPEUTICS INC COM 29337E102 2471100 121073 SH SOLE 121073 0 0 FIRST CTZNS BANCSHARES INC N CL A 31946M103 848360 661 SH SOLE 661 0 0 FIRSTSERVICE CORP NEW COM 33767E202 692019 4491 SH SOLE 4491 0 0 FISERV INC COM 337738108 952811 7553 SH SOLE 7553 0 0 FRONTIER COMMUNICATIONS PARE COM 35909D109 761369 40846 SH SOLE 40846 0 0 GENERAL ELECTRIC CO COM NEW 369604301 749287 6821 SH SOLE 6821 0 0 GERON CORP COM 374163103 393880 122704 SH SOLE 122704 0 0 H WORLD GROUP LTD SPONSORED ADS 44332N106 803870 20729 SH SOLE 20729 0 0 HCA HEALTHCARE INC COM 40412C101 731691 2411 SH SOLE 2411 0 0 HDFC BANK LTD SPONSORED ADS 40415F101 685917 9841 SH SOLE 9841 0 0 HORIZON THERAPEUTICS PUB L SHS G46188101 3595019 34954 SH SOLE 34954 0 0 ICICI BANK LIMITED ADR 45104G104 681944 29547 SH SOLE 29547 0 0 IMMUNEERING CORP CLASS A COM 45254E107 2566535 253110 SH SOLE 253110 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 2643876 44094 SH SOLE 44094 0 0 IMMUNOVANT INC COM 45258J102 3420670 180320 SH SOLE 180320 0 0 INCYTE CORP COM 45337C102 677218 10879 SH SOLE 10879 0 0 INDIVIOR PLC ORD G4766E116 3094000 130000 SH SOLE 130000 0 0 INTUIT COM 461202103 1357617 2963 SH SOLE 2963 0 0 INVESCO DB COMMDY INDX TRCK UNIT 46138B103 32600287 1436136 SH SOLE 1436136 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 468343 66526 SH SOLE 66526 0 0 IVERIC BIO INC COM 46583P102 5489975 139552 SH SOLE 139552 0 0 JD.COM INC SPON ADR CL A 47215P106 1579025 46265 SH SOLE 46265 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 626103 69567 SH SOLE 69567 0 0 KARUNA THERAPEUTICS INC COM 48576A100 1967046 9071 SH SOLE 9071 0 0 KE HLDGS INC SPONSORED ADS 482497104 392144 26407 SH SOLE 26407 0 0 KRYSTAL BIOTECH INC COM 501147102 297022 2530 SH SOLE 2530 0 0 KURA ONCOLOGY INC COM 50127T109 558486 52787 SH SOLE 52787 0 0 LAUREATE EDUCATION INC COMMON STOCK 518613203 858474 71007 SH SOLE 71007 0 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 2511657 36385 SH SOLE 36385 0 0 LI AUTO INC SPONSORED ADS 50202M102 420007 11966 SH SOLE 11966 0 0 LIBERTY GLOBAL PLC SHS CL C G5480U120 722599 40664 SH SOLE 40664 0 0 LITHIA MTRS INC COM 536797103 943045 3101 SH SOLE 3101 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 645876 2796 SH SOLE 2796 0 0 MAGELLAN MIDSTREAM PRTNRS LP COM UNIT RP LP 559080106 3485371 55927 SH SOLE 55927 0 0 MASTERCARD INCORPORATED CL A 57636Q104 1670345 4247 SH SOLE 4247 0 0 MERUS N V COM N5749R100 895931 34027 SH SOLE 34027 0 0 META PLATFORMS INC CL A 30303M102 1690312 5890 SH SOLE 5890 0 0 MICROSOFT CORP COM 594918104 3867853 11358 SH SOLE 11358 0 0 MIRATI THERAPEUTICS INC COM 60468T105 568614 15738 SH SOLE 15738 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 6615822 129722 SH SOLE 129722 0 0 MSCI INC COM 55354G100 679532 1448 SH SOLE 1448 0 0 NATERA INC COM 632307104 353028 7255 SH SOLE 7255 0 0 NETFLIX INC COM 64110L106 724165 1644 SH SOLE 1644 0 0 NEW YORK TIMES CO CL A 650111107 663041 16837 SH SOLE 16837 0 0 NOV INC COM 62955J103 674515 42052 SH SOLE 42052 0 0 NUVALENT INC COM 670703107 3048807 72298 SH SOLE 72298 0 0 OCCIDENTAL PETE CORP COM 674599105 731884 12447 SH SOLE 12447 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 2639252 292276 SH SOLE 292276 0 0 PALO ALTO NETWORKS INC COM 697435105 818909 3205 SH SOLE 3205 0 0 PDD HOLDINGS INC SPONSORED ADS 722304102 403155 5831 SH SOLE 5831 0 0 PENNYMAC FINL SVCS INC NEW COM 70932M107 923662 13137 SH SOLE 13137 0 0 PLIANT THERAPEUTICS INC COM 729139105 616714 34035 SH SOLE 34035 0 0 PNM RES INC COM 69349H107 3152896 69909 SH SOLE 69909 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 805924 29179 SH SOLE 29179 0 0 PROTHENA CORP PLC SHS G72800108 437402 6406 SH SOLE 6406 0 0 PTC INC COM 69370C100 1377607 9681 SH SOLE 9681 0 0 RELAY THERAPEUTICS INC COM 75943R102 404394 32197 SH SOLE 32197 0 0 REPARE THERAPEUTICS INC COM 760273102 1747530 165173 SH SOLE 165173 0 0 ROPER TECHNOLOGIES INC COM 776696106 919770 1913 SH SOLE 1913 0 0 RXO INC COMMON STOCK 74982T103 756792 33383 SH SOLE 33383 0 0 SALESFORCE INC COM 79466L302 2974329 14079 SH SOLE 14079 0 0 SAREPTA THERAPEUTICS INC COM 803607100 573173 5005 SH SOLE 5005 0 0 SEA LTD SPONSORD ADS 81141R100 687251 11841 SH SOLE 11841 0 0 SEAGEN INC COM 81181C104 3659627 19015 SH SOLE 19015 0 0 SEAWORLD ENTMT INC COM 81282V100 744261 13288 SH SOLE 13288 0 0 SPRINGWORKS THERAPEUTICS INC COM 85205L107 306459 11688 SH SOLE 11688 0 0 STONECO LTD COM CL A G85158106 679425 53330 SH SOLE 53330 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 702746 33576 SH SOLE 33576 0 0 TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 673641 6675 SH SOLE 6675 0 0 TECK RESOURCES LTD CL B 878742204 672000 15962 SH SOLE 15962 0 0 TERNS PHARMACEUTICALS INC COM 880881107 1572113 179670 SH SOLE 179670 0 0 THESEUS PHARMACEUTICALS INC COM 88369M101 1275588 136719 SH SOLE 136719 0 0 TRANSDIGM GROUP INC COM 893641100 678675 759 SH SOLE 759 0 0 TRANSOCEAN LTD REG SHS H8817H100 717298 102325 SH SOLE 102325 0 0 TRAVERE THERAPEUTICS INC COM 89422G107 390098 25397 SH SOLE 25397 0 0 TRIP COM GROUP LTD ADS 89677Q107 830515 23729 SH SOLE 23729 0 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 337948 7326 SH SOLE 7326 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 384547 1742 SH SOLE 1742 0 0 VAXCYTE INC COM 92243G108 727176 14561 SH SOLE 14561 0 0 VERONA PHARMA PLC SPONSORED ADS 925050106 719331 34027 SH SOLE 34027 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 2587519 108765 SH SOLE 108765 0 0 VISA INC COM CL A 92826C839 1930000 8127 SH SOLE 8127 0 0 VMWARE INC CL A COM 928563402 4821662 33556 SH SOLE 33556 0 0 WARNER MUSIC GROUP CORP COM CL A 934550203 646484 24779 SH SOLE 24779 0 0 WESCO INTL INC COM 95082P105 894763 4997 SH SOLE 4997 0 0 WORLD WRESTLING ENTMT INC CL A 98156Q108 966142 8907 SH SOLE 8907 0 0 XENON PHARMACEUTICALS INC COM 98420N105 676638 17575 SH SOLE 17575 0 0 XOMA CORP DEL COM NEW 98419J206 2246002 118899 SH SOLE 118899 0 0 XPO INC COM 983793100 1196520 20280 SH SOLE 20280 0 0