X0303 4 2010-03-01 0 0000882095 GILEAD SCIENCES INC GILD 0001334682 Alton Gregg H GILEAD SCIENCES, INC. 333 LAKESIDE DRIVE FOSTER CITY CA 94404 0 1 0 0 EVP, Corp & Med Affairs Common Stock 2010-03-01 4 M 0 5500 15.265 A 23556 D Common Stock 2010-03-01 4 S 0 5500 47.6547 D 18056 D Non-Qualified Stock Option (rght to buy) 15.2650 2010-03-01 4 M 0 5500 0 D 2014-01-28 Common Stock 5500 94500 D The options have a 5 year vesting schedule. 20% of the options vested on January 28, 2005, the first anniversary of the date of the grant. The balance vested 5% every three months thereafter until fully vested on January 28, 2009. The options expire on January 28, 2014. Sale prices reported for the transactions reported here range from $47.45 to $47.70. Full information regarding the number of shares purchased or sold at each separate price will be provided to the SEC, the issuer or its shareowners upon request. The exercise and sale transactions reported in this Form 4 are made pursuant to a Rule 105b-1 trading plan established by Mr. Alton on August 19, 2009. /s/ Gregg H. Alton 2010-03-02