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Condensed Consolidated Statements Of Cash Flows (USD $)
3 Months Ended 120 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Mar. 31, 2012
Operating activities:      
Net loss $ (15,559,218) $ (13,868,207) $ (198,884,719)
Adjustments to reconcile net loss to net cash used in operating activities:      
Non-cash stock-based compensation 828,084 683,693 9,818,740
Depreciation and amortization 33,965 29,903 455,944
Stock issued for license agreement     575,023
Non-cash interest expense     34,020
Gain on disposition of assets     (2,208)
Fair value of warrants for finder's agreement     433,750
Changes in operating assets and liabilities:      
Prepaid contract research and manufacturing expenses, other prepaid expenses and other assets (560,177) (469,677) (1,527,291)
Accounts payable, accrued contract research and manufacturing expenses and other accrued expenses (167,191) 3,618,081 11,651,269
Accrued compensation and related expenses (625,594) (683,934) 793,843
Net cash used in operating activities (16,050,131) (10,690,141) (176,651,629)
Investing activities:      
Acquisitions of property and equipment (20,929) (70,777) (735,402)
Proceeds from sale of assets     3,677
Purchases of short-term investments   (45,128,980) (115,143,906)
Redemptions and sales of short-term investments 4,500,000   115,143,906
Security deposits     (38,267)
Net cash provided by (used in) investing activities 4,479,071 (45,199,757) (769,992)
Financing activities:      
Proceeds from borrowings from affiliate     1,745,000
Proceeds from exercise of stock options   8,372,465 80,729
Proceeds from exercise of common stock warrants     9,054,546
Recapitalization of the Company     (400,000)
Proceeds from sales of equity securities, net of issuance costs 22,145,220 37,770,250 218,543,385
Receipt of recovery of short-swing profits   73,103 73,797
Receipt of cash for stock subscription receivable     4,625
Net cash provided by financing activities 22,145,220 46,215,818 229,102,082
Net increase (decrease) in cash and cash equivalents 10,574,160 (9,674,080) 51,680,461
Cash and cash equivalents, beginning of period 41,106,301 47,593,055  
Cash and cash equivalents, end of period 51,680,461 37,918,975 51,680,461
Supplemental disclosure of cash flow information:      
Cash paid for interest     $ 224,328