CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (USD $)	Total USD ($)	At The Market Equity Offering Program [Member] USD ($)	Common Stock [Member] USD ($)	Common Stock [Member] At The Market Equity Offering Program [Member] USD ($)	Common Stock [Member] Founders [Member] USD ($)	Additional Paid-in Capital [Member] USD ($)	Additional Paid-in Capital [Member] At The Market Equity Offering Program [Member] USD ($)	Additional Paid-in Capital [Member] Founders [Member] USD ($)	Unpaid Subscription On Common Stock [Member] USD ($)	Unpaid Subscription On Common Stock [Member] Founders [Member] USD ($)	Deferred Stock-Based Compensation [Member] USD ($)	Deficit Accumulated During The Development Stage [Member] USD ($)	Exercise Of Common Stock Warrants [Member] USD ($)	Exercise Of Common Stock Warrants [Member] Common Stock [Member] USD ($)	Exercise Of Common Stock Warrants [Member] Additional Paid-in Capital [Member] USD ($)	January [Member] USD ($)	January [Member] Common Stock [Member] USD ($)	January [Member] Additional Paid-in Capital [Member] USD ($)	February [Member] USD ($)	February [Member] Common Stock [Member] USD ($)	February [Member] Additional Paid-in Capital [Member] USD ($)	March [Member] USD ($)	March [Member] License Fee [Member] USD ($)	March [Member] Common Stock [Member] USD ($)	March [Member] Common Stock [Member] License Fee [Member] USD ($)	March [Member] Additional Paid-in Capital [Member] USD ($)	March [Member] Additional Paid-in Capital [Member] License Fee [Member] USD ($)	April [Member] USD ($)	April [Member] License Fee [Member] USD ($)	April [Member] Chief Executives [Member] USD ($)	April [Member] Common Stock [Member] USD ($)	April [Member] Common Stock [Member] License Fee [Member] USD ($)	April [Member] Common Stock [Member] Chief Executives [Member] USD ($)	April [Member] Additional Paid-in Capital [Member] USD ($)	April [Member] Additional Paid-in Capital [Member] License Fee [Member] USD ($)	April [Member] Additional Paid-in Capital [Member] Chief Executives [Member] USD ($)	May [Member] USD ($)	May [Member] License Fee [Member] USD ($)	May [Member] Common Stock [Member] License Fee [Member] USD ($)	May [Member] Additional Paid-in Capital [Member] USD ($)	May [Member] Additional Paid-in Capital [Member] License Fee [Member] USD ($)	June [Member] Exercise Of Common Stock Warrants [Member] USD ($)	June [Member] Exercise Of Common Stock Warrants [Member] Common Stock [Member] USD ($)	June [Member] Exercise Of Common Stock Warrants [Member] Additional Paid-in Capital [Member] USD ($)	July [Member] USD ($)	July [Member] Common Stock [Member] USD ($)	July [Member] Additional Paid-in Capital [Member] USD ($)	September [Member] USD ($)	September [Member] Common Stock [Member] USD ($)	September [Member] Additional Paid-in Capital [Member] USD ($)	October [Member] USD ($)	October [Member] Common Stock [Member] USD ($)	October [Member] Additional Paid-in Capital [Member] USD ($)	October [Member] Exercise Of Common Stock Warrants [Member] USD ($)	October [Member] Exercise Of Common Stock Warrants [Member] Common Stock [Member]	October [Member] Exercise Of Common Stock Warrants [Member] Additional Paid-in Capital [Member] USD ($)	November [Member] USD ($)	November [Member] Common Stock [Member] USD ($)	November [Member] Additional Paid-in Capital [Member] USD ($)	December [Member] USD ($)	December [Member] Common Stock [Member] USD ($)	December [Member] Additional Paid-in Capital [Member] USD ($)
Balance at Apr. 02, 2002
Common stock issued during period					542			4,083		(4,625)
Common stock issued during period, shares					5,428,217
Receipt of cash for stock subscription receivable									4,625
Balance at Dec. 31, 2002
Balance at Dec. 31, 2003			542			4,083			(4,625)
Balance, shares at Dec. 31, 2003			5,428,217
Common stock issued during period																							402		47		355			408			48			360																								13,550,809	554	13,550,255
Common stock issued during period, shares	5,532,994																								471,816								478,330																												5,532,994
Receipt of cash for stock subscription receivable	4,625								4,625
Deferred stock-based compensation						33,525					(33,525)
Amortization of deferred stock-based compensation	1,529										1,529
Net loss	(3,016,559)										0	(3,016,559)
Balance at Dec. 31, 2004	10,541,214		1,191			13,588,578					(31,996)	(3,016,559)
Balance, shares at Dec. 31, 2004			11,911,357
Recapitalization of the Company (See Note 1)	(400,000)		46			(400,046)					0
Recapitalization of the Company (See Note 1), shares			457,168
Employee stock options exercised	999		1			998
Employee stock options exercised, shares			14,663
Adoption of SFAS 123R						(31,996)					31,996
Amortization of deferred stock-based compensation	99,319					99,319
Variable accounting for stock options granted to third party	58,594					58,594
Net loss	(7,915,722)											(7,915,722)
Balance at Dec. 31, 2005	2,384,404		1,238			13,315,447						(10,932,281)
Balance, shares at Dec. 31, 2005			12,383,188
Common stock issued during period																			19,855,652	717	19,854,935																	274,621	6		274,615
Common stock issued during period, shares	7,166,666																			7,166,666																			63,131
Common stock issued cashless																								2		(2)
Common stock issued cashless, shares																								15,461
Employee stock options exercised	5,080		8			5,072
Employee stock options exercised, shares			78,683
Variable accounting for stock options granted to third party	4,192					4,192
Share-Based Compensation	283,983					283,983
Net loss	(8,671,376)											(8,671,376)
Balance at Dec. 31, 2006	14,136,556		1,971			33,738,242						(19,603,657)
Balance, shares at Dec. 31, 2006			19,707,129
Common stock issued during period																						11,476,677		265		11,476,412			150,000			3			149,997							247,000	6	246,994										5,040		5,040	45,754,769	739	45,754,030
Common stock issued during period, shares																								2,648,306								26,643											60,000												1,200			7,388,172
Common stock issued cashless	0		6			(6)
Common stock issued cashless, shares			68,136
Fair value of warrants issued in May 2006 in consideration of finders fee at approximately $1.75 per share for which vesting was conditioned on an even that occurred in January 2007																																					433,750			433,750
Employee stock options exercised	15,706		2			15,704
Employee stock options exercised, shares			17,868
Share-Based Compensation	828,626					828,626
Net loss	(15,081,545)											(15,081,545)
Balance at Dec. 31, 2007	57,966,579		2,992			92,648,789						(34,685,202)
Balance, shares at Dec. 31, 2007			29,917,454
Common stock issued during period													47,040	1	47,039													150,000	150,000		3			149,997
Common stock issued during period, shares														11,200																	30,612
Common stock issued cashless														6	(6)
Common stock issued cashless, shares														57,983
Final adjustment to issuance costs accrued in conjunction with the sale and issuance of common stock																																																									5,733		5,733
Employee stock options exercised	58,944		9			58,935
Employee stock options exercised, shares			94,230
Share-Based Compensation	1,405,752					1,405,752
Net loss	(35,086,151)		0			0						(35,086,151)
Balance at Dec. 31, 2008	24,547,897		3,011			94,316,239						(69,771,353)
Balance, shares at Dec. 31, 2008			30,111,479
Common stock issued during period																																													12,402,758	333	12,402,425
Common stock issued during period, shares																																														3,325,000
Common stock issued cashless														6	(6)
Common stock issued cashless, shares														63,927
Share-Based Compensation	1,673,165					1,673,165
Net loss	(25,771,914)											(25,771,914)
Balance at Dec. 31, 2009	12,851,906		3,350			108,391,823						(95,543,267)
Balance, shares at Dec. 31, 2009			33,500,406
Common stock issued during period													275,331	7	275,324							16,762,923		670		16,762,253																						2,851,376	63	2,851,313	37,789,542	821	37,788,721
Common stock issued during period, shares														65,555										6,700,000																									634,500			8,214,286
Common stock issued cashless	0		68			(68)
Common stock issued cashless, shares			676,228
Share-Based Compensation	1,986,755					1,986,755
Net loss	(37,330,069)											(37,330,069)
Balance at Dec. 31, 2010	35,187,764		4,979			168,056,121						(132,873,336)
Balance, shares at Dec. 31, 2010			49,790,975
Common stock issued during period	8,372,464		199			8,372,265							107,671	4	107,667				37,726,538	1,006	37,725,532
Common stock issued during period, shares			1,993,444											37,277						10,062,500
Common stock issued cashless													0	15	(15)
Common stock issued cashless, shares														149,950
Recovery of short-swing profits, net of expenses	73,797					73,797
Share-Based Compensation	2,648,741					2,648,741
Net loss	(50,452,165)											(50,452,165)
Balance at Dec. 31, 2011	33,664,810		6,203			216,984,108						(183,325,501)
Balance, shares at Dec. 31, 2011			62,034,146
Common stock issued during period																22,151,851	499	22,151,352
Common stock issued during period, shares																	4,989,275
Common stock issued cashless													0	2	(2)
Common stock issued cashless, shares														17,148
Employee stock options exercised	7,194		4			7,190
Employee stock options exercised, shares			35,210
Share-Based Compensation	1,828,204					1,828,204
Net loss	(31,735,909)											(31,735,909)
Balance at Dec. 31, 2012	25,916,150		6,708			240,970,852						(215,061,410)
Balance, shares at Dec. 31, 2012			67,075,779
Common stock issued during period		10,408,288		360			10,407,928																																																		21,359,379	767	21,358,612
Common stock issued during period, shares	3,609,595			3,609,595																																																						7,666,667
Employee stock options exercised	141,012		8			141,004
Employee stock options exercised, shares			81,875
Share-Based Compensation	1,847,076					1,847,076
Net loss	(16,416,233)											(16,416,233)
Balance at Dec. 31, 2013	$ 43,255,672		$ 7,843			$ 274,725,472						$ (231,477,643)
Balance, shares at Dec. 31, 2013			78,433,916