CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS EQUITY (USD $)	February [Member] Common Stock [Member]	February [Member] Additional Paid-In capital [Member]	February [Member]	March [Member] License Fee [Member] Common Stock [Member]	March [Member] License Fee [Member] Additional Paid-In capital [Member]	March [Member] License Fee [Member]	March [Member] Common Stock [Member]	March [Member] Additional Paid-In capital [Member]	March [Member]	April [Member] License Fee [Member] Common Stock [Member]	April [Member] License Fee [Member] Additional Paid-In capital [Member]	April [Member] License Fee [Member]	April [Member] Chief Executive [Member] Common Stock [Member]	April [Member] Chief Executive [Member] Additional Paid-In capital [Member]	April [Member] Chief Executive [Member]	April [Member] Common Stock [Member]	April [Member] Additional Paid-In capital [Member]	April [Member]	May [Member] License Fee [Member] Common Stock [Member]	May [Member] License Fee [Member] Additional Paid-In capital [Member]	May [Member] License Fee [Member]	May [Member] Additional Paid-In capital [Member]	May [Member]	June [Member] Exercise Of Common Stock Warrants [Member] Common Stock [Member]	June [Member] Exercise Of Common Stock Warrants [Member] Additional Paid-In capital [Member]	June [Member] Exercise Of Common Stock Warrants [Member]	July [Member] Common Stock [Member]	July [Member] Additional Paid-In capital [Member]	July [Member]	September [Member] Common Stock [Member]	September [Member] Additional Paid-In capital [Member]	September [Member]	October [Member] Exercise Of Common Stock Warrants [Member] Common Stock [Member]	October [Member] Exercise Of Common Stock Warrants [Member] Additional Paid-In capital [Member]	October [Member] Exercise Of Common Stock Warrants [Member]	October [Member] Common Stock [Member]	October [Member] Additional Paid-In capital [Member]	October [Member]	November [Member] Common Stock [Member]	November [Member] Additional Paid-In capital [Member]	November [Member]	December [Member] Common Stock [Member]	December [Member] Additional Paid-In capital [Member]	December [Member]	January [Member] Common Stock [Member]	January [Member] Additional Paid-In capital [Member]	January [Member]	Exercise Of Common Stock Warrants [Member] Common Stock [Member]	Exercise Of Common Stock Warrants [Member] Additional Paid-In capital [Member]	Exercise Of Common Stock Warrants [Member]	Founders [Member] Common Stock [Member]	Founders [Member] Additional Paid-In capital [Member]	Founders [Member] Unpaid Subscription On Common Stock [Member]	Common Stock [Member]	Additional Paid-In capital [Member]	Unpaid Subscription On Common Stock [Member]	Deferred Stock-Based Compensation [Member]	Deficit Accumulated During The Development Stage [Member]	Total
Balance at Apr. 02, 2002
Common stock issued during period																																																			$ 542	$ 4,083	$ (4,625)
Common stock issued during period, shares																																																			5,428,217
Balance at Dec. 31, 2003																																																						542	4,083	(4,625)
Balance, shares at Dec. 31, 2003																																																						5,428,217
Common stock issued during period				47	355	402							48	360	408																											554	13,550,255	13,550,809
Common stock issued during period, shares				471,816									478,330																													5,532,994																	5,532,994
Receipt of cash for stock subscription receivable																																																								4,625			4,625
Deferred stock-based compensation																																																							33,525		(33,525)
Amortization of deferred stock-based compensation																																																									1,529		1,529
Net loss																																																										(3,016,559)	(3,016,559)
Balance at Dec. 31, 2004																																																						1,191	13,588,578		(31,996)	(3,016,559)	10,541,214
Balance, shares at Dec. 31, 2004																																																						11,911,357
Recapitalization of the Company																																																						46	(400,046)				(400,000)
Recapitalization of the Company (See Note 1), shares																																																						457,168
Employee stock options exercised																																																						1	998				999
Employee stock options exercised, shares																																																						14,663					14,663
Adoption of SFAS 123R																																																							(31,996)		31,996
Amortization of deferred stock-based compensation																																																							99,319				99,319
Variable accounting for stock options granted to third party																																																							58,594				58,594
Net loss																																																										(7,915,722)	(7,915,722)
Balance at Dec. 31, 2005																																																						1,238	13,315,447			(10,932,281)	2,384,404
Balance, shares at Dec. 31, 2005																																																						12,383,188
Common stock issued during period	717	19,854,935	19,855,652																6	274,615	274,621
Common stock issued during period, shares	7,166,666																		63,131																																								7,166,666
Common stock issued cashless							2	(2)
Common stock issued cashless, shares							15,461
Employee stock options exercised																																																						8	5,072				5,080
Employee stock options exercised, shares																																																						78,683					78,683
Variable accounting for stock options granted to third party																																																							4,192				4,192
Share-Based Compensation																																																							283,983				283,983
Net loss																																																										(8,671,376)	(8,671,376)
Balance at Dec. 31, 2006																																																						1,971	33,738,242			(19,603,657)	14,136,556
Balance, shares at Dec. 31, 2006																																																						19,707,129
Common stock issued during period							265	11,476,412	11,476,677	3	149,997	150,000												6	246,994	247,000							0	5,040	5,040				739	45,754,030	45,754,769
Common stock issued during period, shares							2,648,306			26,643														60,000									1,200						7,388,172
Common stock issued cashless																																																						6	(6)
Common stock issued cashless, shares																																																						68,136
Fair value of warrants issued in May 2006 in consideration of finders fee at approximately $1.75 per share for which vesting was conditioned on an even that occurred in January 2007																						433,750	433,750
Employee stock options exercised																																																						2	15,704				15,706
Employee stock options exercised, shares																																																						17,868					17,868
Share-Based Compensation																																																							828,626				828,626
Net loss																																																										(15,081,545)	(15,081,545)
Balance at Dec. 31, 2007																																																						2,992	92,648,789			(34,685,202)	57,966,579
Balance, shares at Dec. 31, 2007																																																						29,917,454
Common stock issued during period																3	149,997	150,000																														1	47,039	47,040
Common stock issued during period, shares																30,612																																11,200
Common stock issued cashless																																																6	(6)
Common stock issued cashless, shares																																																57,983
Final adjustment to issuance costs accrued in conjunction with the sale and issuance of common stock																																								5,733	5,733
Employee stock options exercised																																																						9	58,935				58,944
Employee stock options exercised, shares																																																						94,230					94,230
Share-Based Compensation																																																							1,405,752				1,405,752
Net loss																																																										(35,086,151)	(35,086,151)
Balance at Dec. 31, 2008																																																						3,011	94,316,239			(69,771,353)	24,547,897
Balance, shares at Dec. 31, 2008																																																						30,111,479
Common stock issued during period																											333	12,402,425	12,402,758
Common stock issued during period, shares																											3,325,000
Common stock issued cashless																																																6	(6)
Common stock issued cashless, shares																																																63,927
Share-Based Compensation																																																							1,673,165				1,673,165
Net loss																																																										(25,771,914)	(25,771,914)
Balance at Dec. 31, 2009																																																						3,350	108,391,823			(95,543,267)	12,851,906
Balance, shares at Dec. 31, 2009																																																						33,500,406
Common stock issued during period							670	16,762,253	16,762,923																					63	2,851,313	2,851,376				821	37,788,721	37,789,542										7	275,324	275,331
Common stock issued during period, shares							6,700,000																							634,500						8,214,286												65,555						8,214,286
Common stock issued cashless																																																						68	(68)
Common stock issued cashless, shares																																																						676,228
Share-Based Compensation																																																							1,986,755				1,986,755
Net loss																																																										(37,330,069)	(37,330,069)
Balance at Dec. 31, 2010																																																						4,979	168,056,121			(132,873,336)	35,187,764
Balance, shares at Dec. 31, 2010																																																						49,790,975
Common stock issued during period	1,006	37,725,532	37,726,538																																													4	107,667	107,671				199	8,372,265				8,372,464
Common stock issued during period, shares	10,062,500																																															37,277						1,993,444
Common stock issued cashless																																																15	(15)						(68)
Common stock issued cashless, shares																																																149,950
Recovery of short-swing profits, net of expenses																																																							73,797				73,797
Share-Based Compensation																																																							2,648,741				2,648,741
Net loss																																																										(50,452,165)	(50,452,165)
Balance at Dec. 31, 2011																																																						6,203	216,984,108			(183,325,501)	33,664,810
Balance, shares at Dec. 31, 2011																																																						62,034,146
Common stock issued during period																																													499	22,151,352	22,151,851
Common stock issued during period, shares																																													4,989,275
Common stock issued cashless																																																2	(2)
Common stock issued cashless, shares																																																17,148
Employee stock options exercised																																																						4	7,190				7,194
Employee stock options exercised, shares																																																						35,210					35,210
Share-Based Compensation																																																							1,828,204				1,828,204
Net loss																																																										(31,735,909)	(31,735,909)
Balance at Dec. 31, 2012																																																						$ 6,708	$ 240,970,852			$ (215,061,410)	$ 25,916,150
Balance, shares at Dec. 31, 2012																																																						67,075,779