X0306 4 2017-01-31 0 0001131324 GENOMIC HEALTH INC GHDX 0001333482 Popovits Kimberly J 301 PENOBSCOT DR. REDWOOD CITY CA 94063 1 1 0 0 President and CEO Common Stock 2017-01-31 4 A 0 27760 0.00 A 87380 D Common Stock 12298 I Held by UBS for Benefit of Kimberly Popovits Common Stock 16825 I Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee. Common Stock 200851 I Held by the Popovits 2010 Trust Employee Stock Option (right to buy) Holding 27.48 2017-01-31 4 A 0 191500 0.00 A 2027-01-31 Common Stock 191500 191500 D Restricted stock units awarded on January 31, 2017 which vest as to 1/3 of the shares on each of February 15, 2018, 2019 and 2020. Includes an aggregate of 30,634 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. The option becomes exercisable as to 25% of the shares on January 31, 2018, and becomes exercisable as to 1/48th of the shares each full month thereafter. /s/ Jason W. Radford, Attorney-in-fact 2017-02-02