X0306 4 2015-02-12 0 0001131324 GENOMIC HEALTH INC GHDX 0001333482 Popovits Kimberly J 301 PENOBSCOT DRIVE REDWOOD CITY CA 94403 1 1 0 0 President and CEO Common Stock 2015-02-12 4 M 0 3000 18.89 A 39965 D Common Stock 2015-02-12 4 S 0 3000 29.8553 D 36965 D Common Stock 12298 I Held by UBS for Benefit of Kimberly Popovits Common Stock 16825 I Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee. Common Stock 204601 I Held by the Popovits 2010 Trust Employee Stock Option (right to buy) 18.89 2015-02-12 4 M 0 3000 0.00 D 2016-11-30 Common Stock 3000 21313 D These sales of common stock were effected pursuant to Rule 10b5-1 sales plan adopted by the reporting person on March 10, 2014. Represents weighted average sale price. Actual sale prices ranged from $29.64 to $30.05. Reporting person undertakes to provide upon request by the Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within the range indicated. Includes an aggregate of 22,335 shares of common stock issuable pursuant to previously reported restricted stock unit awards that have not vested. The option became exercisable as to 25% of the shares on November 30, 2007, and becomes exercisable as to 1/48th of the shares each full month thereafter. /s/ Kimberly J. Popovits 2015-02-17