<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.fhlbboston.com/role/Document" xlink:href="fhlbbost-20200129.xsd#Document" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://www.fhlbboston.com/role/Document" xlink:type="extended">
    <link:loc xlink:href="fhlbbost-20200129.xsd#fhlbbost_CoverDocumentAbstract" xlink:label="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:type="locator" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_A0B2781B6D51A2F8B90C87714F75C72D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_AmendmentFlag_A0B2781B6D51A2F8B90C87714F75C72D" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_48F2BD05A95653B8C45187714F853B66" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_DocumentType_48F2BD05A95653B8C45187714F853B66" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_1E18EBBB0EB63520BCFA87714F85D678" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_DocumentPeriodEndDate_1E18EBBB0EB63520BCFA87714F85D678" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_1778EAEF433557440E1887714F855719" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityRegistrantName_1778EAEF433557440E1887714F855719" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_2E292A16DEB55C62F76F87714F85D1E7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityCentralIndexKey_2E292A16DEB55C62F76F87714F85D1E7" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber" xlink:label="loc_dei_EntityFileNumber_24D15CDCEAFF00B3D01E87714F852CD5" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityFileNumber_24D15CDCEAFF00B3D01E87714F852CD5" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_dei_EntityTaxIdentificationNumber_DD2F2BFE8202F5F3DBB987714F8596AD" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityTaxIdentificationNumber_DD2F2BFE8202F5F3DBB987714F8596AD" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_dei_EntityAddressAddressLine1_4878C3715A8F906007D887714F850B6B" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityAddressAddressLine1_4878C3715A8F906007D887714F850B6B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_dei_EntityAddressCityOrTown_E26350F875BCD397004A87714F855121" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityAddressCityOrTown_E26350F875BCD397004A87714F855121" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:label="loc_dei_EntityAddressStateOrProvince_0B1619151EEC8CDD56BE87714F85978B" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityAddressStateOrProvince_0B1619151EEC8CDD56BE87714F85978B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_dei_EntityAddressPostalZipCode_1108F48C6770FFC9828287714F85ECEC" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityAddressPostalZipCode_1108F48C6770FFC9828287714F85ECEC" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode" xlink:label="loc_dei_CityAreaCode_B33843EC9FC9DBD01B2387714F853B5B" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_CityAreaCode_B33843EC9FC9DBD01B2387714F853B5B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber" xlink:label="loc_dei_LocalPhoneNumber_5CAA12BA956ED94A620587714F8510AD" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_LocalPhoneNumber_5CAA12BA956ED94A620587714F8510AD" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_WrittenCommunications" xlink:label="loc_dei_WrittenCommunications_3FBBD07ED24AFFCFEE9487714F858C64" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_WrittenCommunications_3FBBD07ED24AFFCFEE9487714F858C64" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SolicitingMaterial" xlink:label="loc_dei_SolicitingMaterial_5F6EEA8F89457F2BD58C87714F855275" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_SolicitingMaterial_5F6EEA8F89457F2BD58C87714F855275" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_PreCommencementTenderOffer" xlink:label="loc_dei_PreCommencementTenderOffer_D7E004E14E054B10763487714F85C82B" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_PreCommencementTenderOffer_D7E004E14E054B10763487714F85C82B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_17421A730DE8701E337187714F85A367" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_17421A730DE8701E337187714F85A367" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_dei_EntityEmergingGrowthCompany_BA065C4721D51F935E5087714F85B19E" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityEmergingGrowthCompany_BA065C4721D51F935E5087714F85B19E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_dei_EntityIncorporationStateCountryCode_D0A9A20E151A278D8B2F87714F85E02A" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_fhlbbost_CoverDocumentAbstract_5F5799F41A28FCC5826587714F752000" xlink:to="loc_dei_EntityIncorporationStateCountryCode_D0A9A20E151A278D8B2F87714F85E02A" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>
