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Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Operating activities    
Net loss $ (33,091,014) $ (43,450,124)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 2,539,294 1,725,501
Depreciation and amortization 2,047,854 1,135,550
Amortization of discount on long-term debt and convertible notes   17,550,541
Non-cash interest expense 32,180 339,504
Warrant fair value adjustment   (277,715)
Non-cash rent (income) expense   (154,395)
Changes in operating assets and liabilities:    
Accounts receivable - trade and other 262,999 1,540,253
Prepaid expenses and other current assets (267,414) (88,979)
Other non-current assets 1,437,416 2,270,929
Accounts payable 1,353,762 (1,711,787)
Accrued expenses 77,630 (1,000,939)
Accrued compensation (252,436) (85,633)
Operating lease liabilities (290,492)  
Deferred revenue (8,071,920) (1,294,682)
Net cash used in operating activities (34,222,141) (23,501,976)
Investing activities    
Purchases of property, plant and equipment (1,716,208) (769,870)
Net cash used in investing activities (1,716,208) (769,870)
Financing activities    
Principal payments on finance leases   (480,940)
Principal payments on finance leases (696,875)  
Proceeds from issuance of long-term debt 5,000,000  
Refund of principal payments on long-term debt   588,889
Principal payments on long-term debt   (2,433,680)
Payments for debt issuance costs   (392,000)
Proceeds from issuance of Series D preferred stock, net of issuance costs   25,106,896
Proceeds from public offering of common stock, net of underwriting fees and commissions 31,872,808 47,320,584
Payments for offering costs (610,007) (1,628,090)
Proceeds from exercise of stock options and warrants 142,002 286,998
Net cash provided by financing activities 35,707,928 68,368,657
Net increase (decrease) in cash (230,421) 44,096,811
Cash, beginning of period 39,534,985 3,418,979
Cash, end of period 39,304,564 47,515,790
Supplemental disclosure of cash flow information    
Cash paid for interest 705,249 869,033
Cash paid for operating lease liabilities 790,688  
Right of use assets obtained with lease liabilities 354,791  
Purchase of equipment with leases   456,517
Changes in purchases of equipment in accounts payable 187,086 145,473
Purchase of build-to-suit asset with deferred financing obligation   272,656
Reclassification of deferred financing obligation to long-term debt   277,009
Reclassification of financing costs on deferred financing obligation to discount on long-term debt   1,614,466
Accrued tenant improvements and receivable from landlord 936,104  
Conversion of accrued interest to long-term debt   106,558
Conversion of convertible notes and accrued interest into Series D preferred stock   28,877,498
Deferred offering costs incurred but not paid $ 141,314 340,069
Exercise of stock options through exchange of vested stock options   $ 162,156