Note 2 - Basis of Presentation and Summary of Significant Accounting Policies - Impact of Adoption of Topic 842 (Details) - USD ($)	Dec. 31, 2019	Jan. 01, 2019	Dec. 31, 2018
Assets
Property, plant and equipment, net	$ 9,253,965	$ 8,022,974	$ 8,130,708
Operating lease right-of-use assets, net	2,823,430	3,985,071
Liabilities
Deferred rent			2,674,683
Operating leases, Present value of lease liabilities	6,237,361,000	6,659,725
Finance Lease, Present value of lease liabilities	2,300,976,000	2,464,970	828,785
Long-term debt		10,802,757	11,944,549
Stockholders’ equity:
Accumulated deficit	$ (215,239,450)	(167,655,995)	(167,053,897)
Accounting Standards Update 2016-02 [Member]
Assets
Property, plant and equipment, net			(107,734)
Operating lease right-of-use assets, net			3,985,071
Liabilities
Deferred rent			(2,674,683)
Operating leases, Present value of lease liabilities			6,659,725
Finance Lease, Present value of lease liabilities			1,636,185
Long-term debt			(1,141,792)
Stockholders’ equity:
Accumulated deficit		$ (600,000)	$ (602,098)