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For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Face amount or stated value per share of preferred stock nonredeemable or redeemable solely at the option of the issuer.

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Note 2 - Basis of Presentation and Summary of Significant Accounting Policies (Details Textual)				1 Months Ended	3 Months Ended	12 Months Ended
	Oct. 26, 2018 USD ($)	Jul. 19, 2018	Dec. 22, 2017	Mar. 31, 2018 USD ($)	Dec. 31, 2018 USD ($)	Dec. 31, 2019 USD ($) $ / shares	Dec. 31, 2018 USD ($)	Jan. 01, 2019 USD ($)	Jan. 01, 2018 USD ($)
Cash Equivalents, at Carrying Value, Total					$ 0	$ 0	$ 0
Accounts Receivable, Allowance for Credit Loss, Current					0	0	0
Revenue from Contract with Customer, Excluding Assessed Tax, Total						8,072,120	2,706,981
Accounts Receivable, after Allowance for Credit Loss, Current, Total					272,557		272,557
Lease Liability						8,538,337,000
Retained Earnings (Accumulated Deficit), Ending Balance					(167,053,897)	$ (215,239,450)	$ (167,053,897)	$ (167,655,995)
Number of Operating Segments						1
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent			35.00%			21.00%	21.00%
Tax Cuts and Jobs Act, Change in Tax Rate, Deferred Tax Asset, Income Tax Expense					14,100,000
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount					(14,100,000)	$ 11,178,295
Series D Preferred Stock [Member]
Preferred Stock, Par or Stated Value Per Share \| $ / shares						$ 0.001
Prepaid Expenses and Other Current Assets [Member]
Deferred Offering Costs					110,365	$ 0	$ 110,365
Accounting Standards Update 2016-02 [Member]
Right-of-Use Asset								6,400,000
Lease Liability								9,100,000
Retained Earnings (Accumulated Deficit), Ending Balance					(602,098)		(602,098)	$ (600,000)
Accounting Standards Update 2014-09 [Member]
Retained Earnings (Accumulated Deficit), Ending Balance									$ (500,000)
GlaxoSmithKline [Member]
Revenue from Contract with Customer, Excluding Assessed Tax, Total						8,100,000	400,000
Accounts Receivable, after Allowance for Credit Loss, Current, Total					$ 0	$ 0	$ 0
Credit Concentration Risk [Member] \| Cash Held on Deposit [Member] \| Pacific Western Bank [Member]
Concentration Risk, Percentage						100.00%
Customer Concentration Risk [Member] \| Revenue from Contract with Customer Benchmark [Member] \| GlaxoSmithKline [Member]
Concentration Risk, Percentage						100.00%	15.00%
Customer Concentration Risk [Member] \| Accounts Receivable [Member] \| GlaxoSmithKline [Member]
Concentration Risk, Percentage						0.00%	0.00%
Reverse Stock Split [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio		16.827
Pacific Western Bank Note, A&R LSA [Member]
Debt Instrument Agreement, Minimum Cash Balance To Be Maintained	$ 8,500,000			$ 8,000,000		$ 8,500,000