X0306 4 2018-02-13 0 0001636050 Axovant Sciences Ltd. AXON 0001329646 Bickerstaff George C/O AXOVANT SCIENCES, INC. 11 TIMES SQUARE, 33RD FLOOR NEW YORK NY 10036 1 0 0 0 Stock Option (Right to Buy) 1.81 2018-02-13 4 A 0 150000 0.00 A 2028-02-12 Common Shares 150000 150000 D The common shares underlying this option vest over a period of three years, with one-third of the common shares vesting on each of the first, second and third anniversaries of February 11, 2018, the date of the Reporting Person's appointment to the Issuer's Board of Directors. The option allows for early exercise, subject to the Issuer's repurchase option with respect to any unvested common shares. All common shares underlying such option will become fully vested upon a change in control, as that term is defined in the Issuer's 2015 Equity Incentive Plan. /s/ Stephen Mohr, Attorney-in-Fact 2018-02-15