Condensed Consolidated Statements of Operations (unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Revenues:
Total revenues	$ 7,565	$ 2	$ 10,118	$ 2
Costs and operating expenses:
Cost of product sales	73	0	98	0
Research and development	9,806	7,176	16,994	14,264
Selling, general and administrative, net	27,699	13,115	54,062	22,259
Total costs and operating expenses	37,578	20,291	71,154	36,523
Loss from operations	(30,013)	(20,289)	(61,036)	(36,521)
Interest and other income, net	1,132	222	2,010	426
Interest expense	(5,112)	(729)	(9,938)	(729)
Loss before income taxes	(33,993)	(20,796)	(68,964)	(36,824)
Benefit for income taxes	0	(51)	0	(51)
Net loss	$ (33,993)	$ (20,745)	$ (68,964)	$ (36,773)
Net loss per share, basic and diluted (in dollars per share)	$ (1.26)	$ (0.93)	$ (2.61)	$ (1.65)
Weighted average shares used in computing net loss per share, basic and diluted (in shares)	27,040	22,392	26,454	22,300
Product sales
Revenues:
Total revenues	$ 7,565	$ 0	$ 10,118	$ 0
License and grant revenue
Revenues:
Total revenues	$ 0	$ 2	$ 0	$ 2