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Condensed Consolidated Statements of Operations (unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Income Statement [Abstract]        
License and grant revenue $ 1 $ 138 $ 3 $ 535
Operating expenses        
Research and development 6,459 7,437 20,723 24,183
Selling, general and administrative, net 16,064 7,344 38,323 22,043
Total operating expenses 22,523 14,781 59,046 46,226
Loss from operations (22,522) (14,643) (59,043) (45,691)
Interest and other income, net 839 249 1,265 593
Interest expense (1,677) 0 (2,406) 0
Loss before income taxes (23,360) (14,394) (60,184) (45,098)
Benefit for income taxes 0 0 (51) 0
Net loss $ (23,360) $ (14,394) $ (60,133) $ (45,098)
Net loss per share, basic and diluted (in dollars per share) $ (1.04) $ (0.66) $ (2.69) $ (2.09)
Weighted average shares used in computing net loss per share, basic and diluted (in shares) 22,569 21,941 22,390 21,616