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Stockholders' Equity (Details)
9 Months Ended
Jan. 06, 2016
USD ($)
$ / shares
shares
Sep. 30, 2017
USD ($)
vote
shares
Sep. 30, 2016
USD ($)
May 31, 2017
USD ($)
Jan. 31, 2017
shares
Dec. 31, 2016
shares
Mar. 31, 2016
shares
Shareholders' Equity              
Authorized shares of common stock (in shares)   100,000,000       100,000,000  
Dividends declared | $   $ 0          
Number of votes per share | vote   1          
Net proceeds from follow-on public offering | $   $ 0 $ 61,822,000        
Total common stock reserved for future issuance (in shares)   8,775,213       7,927,394  
Cowen              
Shareholders' Equity              
At-the-market offering, aggregate offering price (up to) | $       $ 50,000,000.0      
At-the-market offering, commission as a percentage of gross proceeds (up to)       3.00%      
2016 Inducement Plan              
Shareholders' Equity              
Total common stock reserved for future issuance (in shares)         900,000   450,000
Employee Stock Purchase Plan              
Shareholders' Equity              
Total common stock reserved for future issuance (in shares)   718,210       532,849  
Stock options              
Shareholders' Equity              
Total common stock reserved for future issuance (in shares)   5,926,814       5,483,557  
Stock options | 2014 Equity Incentive Plan              
Shareholders' Equity              
Authorized for future issuance (in shares)   1,700,824       1,576,926  
Stock options | 2016 Inducement Plan              
Shareholders' Equity              
Authorized for future issuance (in shares)   429,365       334,062  
Common Stock              
Shareholders' Equity              
Sale of shares under the sales agreement (in shares) 2,875,000            
Share price (in dollars per share) | $ / shares $ 23            
Net proceeds from follow-on public offering | $ $ 61,800,000            
Common Stock | Stock options | Over-Allotment Option              
Shareholders' Equity              
Sale of shares under the sales agreement (in shares) 375,000