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Condensed Consolidated Statements of Operations (unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Income Statement [Abstract]        
Revenue $ 2 $ 222 $ 2 $ 397
Operating expenses        
Research and development 7,176 9,224 14,264 16,746
General and administrative, net 13,115 8,058 22,259 14,699
Total operating expenses 20,291 17,282 36,523 31,445
Loss from operations (20,289) (17,060) (36,521) (31,048)
Interest and other income, net 222 184 426 344
Interest expense (729) 0 (729) 0
Loss before income taxes (20,796) (16,876) (36,824) (30,704)
Benefit for income taxes (51) 0 (51) 0
Net loss $ (20,745) $ (16,876) $ (36,773) $ (30,704)
Net loss per share, basic and diluted (in dollars per share) $ (0.93) $ (0.78) $ (1.65) $ (1.43)
Weighted average shares used in computing net loss per share, basic and diluted (in shares) 22,392 21,650 22,300 21,452