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Stock-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2017
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of allocation of total stock-based compensation expense
The following table reflects stock-based compensation expense recognized for the three and six months ended June 30, 2017 and 2016 (in thousands):
 
Three Months Ended
 June 30,
 
Six Months Ended
 June 30,
 
2017
 
2016
 
2017
 
2016
Research and development:
 

 
 

 
 
 
 
Employees
$
849

 
$
691

 
$
1,624

 
$
1,276

Non-employee consultants
46

 
40

 
92

 
122

General and administrative:
 

 
 

 
 
 
 

Employees
2,870

 
1,877

 
4,921

 
3,710

Non-employee consultants
—

 
23

 
12

 
76

Total expense
$
3,765

 
$
2,631

 
$
6,649

 
$
5,184