<?xml version="1.0" encoding="UTF-8"?><own:edgarSubmission xmlns:com="http://www.sec.gov/edgar/common" xmlns:own="http://www.sec.gov/edgar/ownership">
  <!-- Generated by Workiva -->
  <own:headerData>
    <own:submissionType>144</own:submissionType>
    <own:filerInfo>
      <own:filer>
        <own:filerCredentials>
          <own:cik>0001773301</own:cik>
          <own:ccc>XXXXXXXX</own:ccc>
        </own:filerCredentials>
      </own:filer>
      <own:liveTestFlag>LIVE</own:liveTestFlag>



    </own:filerInfo>
  </own:headerData>
  <own:formData>
    <own:issuerInfo>
      <own:issuerCik>0001327567</own:issuerCik>
      <own:issuerName>Palo Alto Networks, Inc.</own:issuerName>
      <own:secFileNumber>001-35594</own:secFileNumber>
      <own:issuerAddress>
        <com:street1>3000 Tannery Way</com:street1>
        <com:city>Santa Clara</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>95054</com:zipCode>
      </own:issuerAddress>
      <own:issuerContactPhone>408-753-4000</own:issuerContactPhone>
      <own:nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Aparna Bawa</own:nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <own:relationshipsToIssuer>
        <own:relationshipToIssuer>Affiliate</own:relationshipToIssuer>
      </own:relationshipsToIssuer>
    </own:issuerInfo>
    <own:securitiesInformation>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:brokerOrMarketmakerDetails>
        <own:name>J.P. Morgan Securities LLC</own:name>
        <own:address>
          <com:street1>270 Park Avenue</com:street1>
          <com:street2>10th Floor</com:street2>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10017</com:zipCode>
        </own:address>
      </own:brokerOrMarketmakerDetails>
      <own:noOfUnitsSold>750</own:noOfUnitsSold>
      <own:aggregateMarketValue>294975</own:aggregateMarketValue>
      <own:noOfUnitsOutstanding>818000000</own:noOfUnitsOutstanding>
      <own:approxSaleDate>09/24/2026</own:approxSaleDate>
      <own:securitiesExchangeName>Nasdaq</own:securitiesExchangeName>
    </own:securitiesInformation>
    <own:securitiesToBeSold>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:acquiredDate>09/01/2024</own:acquiredDate>
      <own:natureOfAcquisitionTransaction>Transfer</own:natureOfAcquisitionTransaction>
      <own:nameOfPersonfromWhomAcquired>Aparna Bawa who acquired the shares via RSU award from the issuer on 09/01/25</own:nameOfPersonfromWhomAcquired>
      <own:isGiftTransaction>N</own:isGiftTransaction>
      <own:amountOfSecuritiesAcquired>107</own:amountOfSecuritiesAcquired>
      <own:paymentDate>09/01/2024</own:paymentDate>
      <own:natureOfPayment>N/A</own:natureOfPayment>
    </own:securitiesToBeSold>
    <own:securitiesToBeSold>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:acquiredDate>03/01/2025</own:acquiredDate>
      <own:natureOfAcquisitionTransaction>Transfer</own:natureOfAcquisitionTransaction>
      <own:nameOfPersonfromWhomAcquired>Aparna Bawa who acquired the shares via RSU award from the issuer on 09/01/24</own:nameOfPersonfromWhomAcquired>
      <own:isGiftTransaction>N</own:isGiftTransaction>
      <own:amountOfSecuritiesAcquired>643</own:amountOfSecuritiesAcquired>
      <own:paymentDate>03/01/2025</own:paymentDate>
      <own:natureOfPayment>N/A</own:natureOfPayment>
    </own:securitiesToBeSold>
    <own:nothingToReportFlagOnSecuritiesSoldInPast3Months>N</own:nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>09/15/2026</own:saleDate>
      <own:amountOfSecuritiesSold>28</own:amountOfSecuritiesSold>
      <own:grossProceeds>10561.04</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>09/15/2026</own:saleDate>
      <own:amountOfSecuritiesSold>472</own:amountOfSecuritiesSold>
      <own:grossProceeds>178028.96</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>09/14/2026</own:saleDate>
      <own:amountOfSecuritiesSold>540</own:amountOfSecuritiesSold>
      <own:grossProceeds>201746.7</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>09/14/2026</own:saleDate>
      <own:amountOfSecuritiesSold>460</own:amountOfSecuritiesSold>
      <own:grossProceeds>171858.30</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>06/22/2026</own:saleDate>
      <own:amountOfSecuritiesSold>345</own:amountOfSecuritiesSold>
      <own:grossProceeds>100086.54</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>06/29/2026</own:saleDate>
      <own:amountOfSecuritiesSold>632</own:amountOfSecuritiesSold>
      <own:grossProceeds>201355.05</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Bawa Family Trust</own:name>
        <own:address>
          <com:street1>Care of Palo Alto Networks, Inc.</com:street1>
          <com:street2>3000 Tannery Way</com:street2>
          <com:city>Santa Clara</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95054</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Common</own:securitiesClassTitle>
      <own:saleDate>07/01/2026</own:saleDate>
      <own:amountOfSecuritiesSold>290</own:amountOfSecuritiesSold>
      <own:grossProceeds>101115.11</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:remarks>The shares represented on this filing are being sold by The Bawa Family Trust, Aparna Bawa as Trustee.</own:remarks>
    <own:noticeSignature>
      <own:noticeDate>09/24/2026</own:noticeDate>
      <own:signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Aparna Bawa</own:signature>
    </own:noticeSignature>
  </own:formData>
</own:edgarSubmission>
