Income Taxes - Schedule of Overall Effective Income Tax Rate (Details)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Tax Disclosure [Abstract]
Income tax benefit based on the federal statutory rate (as a percent)	21.00%	21.00%	21.00%
State income taxes, net of federal benefit (as a percent)	4.40%	35.70%	(2.10%)
Nondeductible expenses (as a percent)	3.20%	(3.20%)	(3.10%)
Change in valuation allowance (as a percent)	2.40%	(49.90%)	(3.10%)
Stock-based compensation (as a percent)	(8.60%)	(23.20%)	(10.50%)
Research and development tax credits (as a percent)	(20.10%)	25.10%	0.00%
Effective Income Tax Rate Reconciliation, Tax Contingency, Percent	(2.80%)	0.00%	0.00%
Goodwill impairment (as a percent)	0.00%	(5.50%)	0.00%
Overall effective income tax rate (as a percent)	(0.50%)	0.00%	2.20%