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Net Loss Per Shares (Details 2) - shares
shares in Thousands
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Anti-dilutive shares excluded from the calculation of diluted net loss per share attributable to common stockholders    
Total shares excluded from net loss per share 18,728 21,454
Options to purchase common stock    
Anti-dilutive shares excluded from the calculation of diluted net loss per share attributable to common stockholders    
Total shares excluded from net loss per share 10,884 14,564
Common stock warrants    
Anti-dilutive shares excluded from the calculation of diluted net loss per share attributable to common stockholders    
Total shares excluded from net loss per share 1,459 1,459
Non-vested restricted stock unit awards    
Anti-dilutive shares excluded from the calculation of diluted net loss per share attributable to common stockholders    
Total shares excluded from net loss per share 6,385 5,431