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Collaboration Agreement - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended
May 31, 2021
Mar. 31, 2022
Mar. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]      
Future milestone payments receivable $ 135,000    
Deferred Revenue   $ 8,300  
Deferred Revenue Related to Development Activities   3,100  
Collaboration revenue   5,367  
Clinical Supply Agreement      
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]      
Upfront payment received $ 12,000    
Upfront payment recognition in future periods to settlement of obligation   $ 12,000  
Deferred revenue, description   Under the LianBio License Agreement, in order to evaluate the transaction price for purposes of ASC 606, the Company determined that the upfront payment of $12.0 million and the reimbursable cost of the clinical supply of LYR-210 constitute the entirety of the consideration to be included in the transaction price as of the outset of the arrangement, which was allocated to the two performance obligations. The potential milestone payments that the Company is eligible to receive were excluded from the transaction price, as all milestone amounts were fully constrained based on the probability of achievement.  
Performance Obligations      
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]      
Collaboration revenue   $ 400 $ 0
Milestone Achievements      
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]      
Collaboration revenue   $ 5,000 $ 0