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Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Income Statement [Abstract]        
Collaboration revenue $ 183,000 $ 598,000 $ 366,000 $ 1,130,000
Operating expenses:        
Research and development 5,110,000 13,264,000 9,986,000 31,502,000
General and administrative 3,501,000 5,139,000 6,764,000 10,957,000
Impairment of property and equipment 0 1,883,000 0 1,883,000
Impairment of right-of-use assets 0 22,836,000 0 22,836,000
Restructuring and other related charges 398,000 6,450,000 1,283,000 6,450,000
Total operating expenses 9,009,000 49,572,000 18,033,000 73,628,000
Loss from operations (8,826,000) (48,974,000) (17,667,000) (72,498,000)
Other income:        
Interest income 410,000 855,000 708,000 1,941,000
Other income 981,000 0 981,000 0
Total other income 1,391,000 855,000 1,689,000 1,941,000
Loss before income tax expense (7,435,000) (48,119,000) (15,978,000) (70,557,000)
Income tax expense (2,000) (12,000) (6,000) (26,000)
Net loss (7,437,000) (48,131,000) (15,984,000) (70,583,000)
Unrealized holding loss on short-term investments, net of tax 0 (29,000) 0 (37,000)
Comprehensive loss $ (7,437,000) $ (48,160,000) $ (15,984,000) $ (70,620,000)
Net loss per share attributable to common stockholders- basic $ (5.51) $ (36.76) $ (12) $ (54.51)
Net loss per share attributable to common stockholders- diluted $ (5.51) $ (36.76) $ (12) $ (54.51)
Weighted-average common shares outstanding-basic 1,348,630 1,309,193 1,331,985 1,294,790
Weighted-average common shares outstanding-diluted 1,348,630 1,309,193 1,331,985 1,294,790