Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Cash flows from operating activities:
Net loss	$ (93,435)	$ (62,680)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation	6,716	5,887
Depreciation expense	471	278
Impairment of property and equipment	1,883	1,592
Write-off of deferred financing costs	140
Impairment of right-of-use assets	22,836
Net amortization of discount on short-term investments	(2,276)	(3,496)
Changes in assets and liabilities:
Prepaid expenses and other current assets	(380)	867
Operating lease right-of-use assets	1,353	(5,137)
Other assets	1,111	210
Accounts payable	(1,887)	450
Accrued expenses and other current liabilities	(5,975)	1,491
Restructuring liability	4,347
Operating lease liabilities	(3,381)	(1,208)
Deferred revenue	(1,534)	(1,558)
Net cash used in operating activities	(70,011)	(63,304)
Cash flows from investing activities:
Purchases of property and equipment	(2,338)	(1,047)
Purchases of short-term investments	(47,949)	(122,423)
Maturity of short-term investments	130,592	110,886
Net cash provided by (used in) investing activities	80,305	(12,584)
Cash flows from financing activities:
Proceeds from sale of common stock, warrants and pre-funded warrants	8,818	69,242
Payment of deferred offering costs	(290)	(3,654)
Proceeds from exercise of stock options	3	103
Net cash provided by financing activities	8,531	65,691
Net increase (decrease) in cash, cash equivalents and restricted cash	18,825	(10,197)
Cash and cash equivalents and restricted cash, beginning of period	23,745	33,942
Cash and cash equivalents and restricted cash, end of period	42,570	23,745
Supplemental disclosure of non-cash financing and investing activities:
Property and equipment purchases included in accounts payable and accrued expenses		623
Prepaid expenses for right-of-use asset included in operating lease liabilities		2,786
Modification of lease agreement		4,931
Other assets included in accounts payable and other current liabilities	$ 13,667
Right-of-use asset in exchange for lease liability		$ 18,156